Saffron's two main active compounds are safranal and crocin.

Our standardized Safranal extract is from Saffron, the most expensive spice on earth.

Note that we also provide a standardized Crocin extract which is available from Gardenia.

Macular Wellness formulas allow you to take a different carotenoid at each meal to support absorption.

The carotenoids compete for absorption, so avoid supplementing Beta Carotene at the same meal.

Also, avoid supplements with stearates or stearic acid listed as 'Other Ingredients.'

Each vegicap supplies:

Nutritional Factors:

 Vitamin B9 (Folate as 5-MTHF) 400 mcg 100%

 Vitamin B12 (as Adenosyl & Methyl Cobalamin) 6 mcg 250%

We emphasize the mitochondrial coenzyme form and keep Methyl B12 to a minimum essential level because Methyl B12 is the catalyst that methylates Mercury. Research shows that "...methylation proceeded at a remarkably high rate when methylcobalamin and inorganic mercury were mixed." Source: Chemical methylation of inorganic mercury with methylcobalamin, a vitamin B12 analog

 Vitamin B15: TMG (Trimethylglycine) (Beta spp.) 10 mg*

Trimethylglycine is a methyl donor with three methyl groups.

 Vitamin B20: ALCAR (Acetyl L-Carnitine) 5 mg*

"L-carnitine and its derivatives are involved in numerous physiological reactions, including sugar aerobic metabolism, oxidative phosphorylation, fatty acid oxidation and osmosis.... L-carnitine has also demonstrated antioxidant properties in animal models of oxidative damage." Source: The aging eye and the role of L-carnitine and its derivatives

 Vitamin C (from 50 mg Ascorbyl Palmitate) 21 mg 24%

The lipophilic AP was able to cross biological barriers and satisfied the tissue demand for ascorbate better than the hydrophilic form. AP should be considered as the preferred form of transport of ascorbate into neural tissues. Source: Ascorbyl palmitate as a carrier of ascorbate into neural tissues

 Coenzyme Q10 (Ubiquinone) 10 mg*

 PQQ (Pyrroloquinoline Quinone) 5 mg*

 Magnesium (from Magnesium Taurate) 4 mg 1%

 Taurine (from Magnesium Taurate) 46 mg*

 N-Acetyl Cysteine (NAC) 20 mg*

 L-Carnosine 24 mg*

"Carnosine (beta-alanyl-L-histidine) has protective functions additional to anti-oxidant and free-radical scavenging roles. It extends cultured human fibroblast life-span, ... protects cells against aldehydes ... and inhibits, in vitro, protein glycation (formation of cross-links, carbonyl groups and AGEs) and DNA/protein cross-linking. Carnosine is an aldehyde scavenger, a likely lipofuscin (age pigment) precursor..." Source: Carnosine, a protective, anti-ageing peptide?

 Reduced Glutathione & S-Acetyl GSH 10 mg each*

Reduced Glutathione is preferable to common Glutathione supplements but is subject to digestion in the gut and in the blood on the way to the retina. We use the more precious S-Acetyl Glutathione form because the addition of the acetyl group not only facilitates crossing the blood-eye barrier but also prevents its digestion until it is taken into the intracellular space, where an enzyme cleaves it off, releasing pre-formed reduced Glutathione into the cytoplasm.

 Stabilized R-Lipoic Acid 10 mg*

We use the patented Stabilized Bio-Enhanced® R-Lipoate form because it is many times more bioavailable than the common natural R-Lipoic Acid or synthetic racemic Lipoic Acid forms that can also harbor toxic impurities.

Botanical Factors:

 Oligomeric Proanthocyanidins (Vitis vinifera) 15 mg*

 Safranal 3% (Crocus sativus) 30 mg*

 Trans-Resveratrol (Polygonum cuspidatum) 20 mg*

 Quercetin Dihydrate (Sophora japonica) 15 mg*

We use the water-soluble Dihydrate form of Quercetin because it is about eight times more bioavailable than common Quercetin.

 Tetrahydrocurcumin & Curcumin (Curcuma longa) 20 mg*

 Polyphenols (Camellia sinensis) 15 mg*

 Ginsenosides 80% (Panax ginseng) 7 mg*

 Salvianolic Acid 20% (Salvia miltiorrhiza) 20 mg*

 C3G 40% (Oryza sativa) 15 mg*

Bioavailability Factors (Proprietary Formula) 34.5 mg*:

 Vitamin B13: Phosphatides 50% (Helianthus annuus)

 Humic & Fulvic Acids

 Moringa 100:1 (Moringa oleifera)

 Gingerol 10% (Zingiber officinale)

 Piperine (Piper nigrum)

 EGb 761 (Ginkgo biloba) (24% Flavone Glycosides, 6% Lactones, <0.0005% Ginkgolic Acid)

 Vitamin B3 (as Niacin) 5 mg 31%

 Vinpocetine (Vinca minor)

 Licorice (Glycyrrhiza glabra)

 Spirit Minerals (ORMUS)

Our Bioavailability Blend supplies 21 master ingredients, including 11 Spirit Minerals, formulated to:

• increase the aqueous solubility of fat-soluble phytonutrients

• support the integrity of the intestinal mucosa, the vascular endothelium, and the blood-brain barrier, and the similar blood-eye barrier, to enhance the selectivity of absorption, transport, and ultimate bioavailability of essential nutrients and phytonutrients to the target tissues and cells.

• stimulate local circulation in the small intestine to increase nutrient absorption into the blood

• increase circulatory perfusion in the eye, brain, and challenging areas of the body to enhance tissue delivery of nutrients

• support and stimulate the sentient, immortal spirit body to regulate and accelerate the body's self-healing processes.

The Fibonacci sequence's mathematics seen in living systems and healing processes inspires the Bioavailability Blend's overarching design. This pattern is a blueprint found throughout the nature of the living universe.

*Daily Value not established.

Serving size: 1 vegicap. Servings per container: 30. Contents: 30 vegicaps.

Directions: 1 to 3 capsules daily with meals away from other carotenoids, or as guided.

Other ingredients: Pullulan Vegicaps (Aureobasidium pullulan), Healing Energy, Love & Prayer.